Congratulations to Paige Shipman, Dr. Bhuvan Yathavan, and co-authors, Dr. Amarbir Gill, Chelsea Pollard, and Drs. Kash Yellepeddi, Hamid Ghandehari, Jeremiah Alt, Abby Pulsipher, and Kristine Smith, for publishing their manuscript, “Quantification of Budesonide Retained in the Sinonasal Cavity After High-Volume Saline Irrigation in Post-Operative Chronic Rhinosinusitis,” in the American Journal of Rhinology and Allergy (March 2024). Their findings demonstrate that the retained dose of budesonide in patients with chronic rhinosinusitis (CRS) after high-volume saline irrigation (HVSI) is significantly higher than previously estimated and decreases with time post-endoscopic sinus surgery. Given that budesonide HVSI is a cornerstone of care in CRS, defining the retained dose and the potential systemic implications is critical to understanding the safety of budesonide HVSI.
For more details, check out Paige, Bhuvan, and colleagues’ article!
