PUBLICATIONS
Most Recent
Mahomva CR, Smith KA, Minkah PAB, Witt BL, Oakley GM, Orlandi RR, Chemokine CCL19 and Its Receptors CCR7 and CCRL1 in Chronic Rhinosinusitis. J Inflamm Res. 2024;2024(17):2991-3002.
PMID: DOI: 10.2147/JIR.S453567
Massey CJ, Oakley GM, Orlandi RR, Ashby S, An eosinophil peroxidase activity assay predicts acute exacerbations in post-operative chronic rhinosinusitis. Int Forum Allergy Rhinol. 2024;accepted.
PMID: DOI:
Shipman PA, Yathavan B,Quantification of budesonide retained in the sinonasal cavity after high-volume saline irrigation in post-operative chronic rhinosinusitis. Am J Rhinol Allergy. 2024;38(3):169-177.
PMID: 38456692 DOI: 10.1177/19458924241237839
Yathavan B,Matrix-mediated delivery of silver nanoparticles for prevention of Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation in chronic rhinosinusitis. Pharmaceutics. 2023;15(10):2426.
PMID: 37353160 DOI: 10.3390/pharmaceutics15102426
Yathavan B, Ellis A, Jedrzkiewicz J, Subrahmanyam N, Khurana N, Pulsipher A, Alt JA, Ghandehari H. Systemic administration of budesonide in pegylated liposomes for improved efficacy in chronic rhinosinusitis. J Control Release. 2023;360:274-284.
PMID: 10610389 DOI: 10.1016/j.jconrel.2023.06.030
Smith KA, Gill AS, Pollard CE, Sumsion JS, Saffari H, Ashby S, Witt BL, Shipman PA, Gabrielsen DA, Yim MT, Levy JM, Oakley GM, Orlandi RR, Gleich GJ, Alt JA, Pulsipher A. An eosinophil peroxidase activity assay accurately predicts eosinophilic chronic rhinosinusitis. J Allergy Clin Immunol. 2023;152(2):400-407.
PMID: 37148919 DOI: 10.1016/j.jaci.2023.04.012
Khurana N, Babajanian E, McCrary H, Pulsipher A, Ghandehari H, Alt JA, Cannon RB. Vascular permeability in HPV+ oropharyngeal cancers aids in fluorescent image-guided transoral robotic surgery using indocyanine green. Head Neck. 2023;45(7):1728-1740.
PMID: 37158163 DOI: 10.1002/hed.27384
Gill AS, Alt JA, Pulsipher A, Smith KA, Subrahmanyam NB, Sumsion JS, Jacob J, Milash BA, Orlandi RR. Topographic distribution of gene expression and sinonasal inflammation in chronic rhinosinusitis without nasal polyposis. Clin Exp Allergy. 2022;52(5):719-722.
PMID: 35218263 DOI: 10.1111/cea.14119
Gill AS, Pulsipher A, Sumsion JS, Howe H, Alt JA. Comorbid asthma may be associated with local inflammatory profile switching among patients with chronic rhinosinusitis without nasal polyposis. Int Forum Allergy Rhinol. 2022;12(5):784-787.
PMID: 34821066 DOI: 10.1002/alr.22917
Khurana N, Yathavan B, Jedrzkiewicz J, Gill AS, Pulsipher A, Alt JA, Ghandehari H. Vascular permeability in chronic rhinosinusitis enhances accumulation and retention of nanoscale pegylated liposomes. Nanomedicine. 2021;38:102453.
PMID: 34363985 DOI: 10.1016/j.nano.2021.102453
Khurana N, Pulsipher A, Jedrzkiewicz J, Ashby S, Pollard CE, Ghandehari H, Alt JA. Inflammation-driven vascular dysregulation in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2021;11(6):976-983.
PMID: 33135871 DOI: 10.1002/alr.22723
Blight BJ, Gill AS, Sumsion JS, Pollard CE, Ashby S, Oakley GM, Alt JA, Pulsipher A. Cell Adhesion Molecules are Upregulated and May Drive Inflammation in Chronic Rhinosinusitis with Nasal Polyposis. J Asthma Allergy. 2021;14:585-593.
PMID: 34079296 DOI: 10.2147/JAA.S307197
Gill AS, Pulsipher A, Sumsion JS, Oakley GM, Leclair LW, Howe H, Orlandi RR, Alt JA. Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status. J Asthma Allergy. 2021;14:405-413.
PMID: 33911879 DOI: 10.2147/JAA.S301825
Pulsipher A, Savage JR, Kennedy TP, Gupta K, Cuiffo BG, Sonis ST, Lee WY. GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling. PLoS One. 2021;16(3):e0249343.
PMID: 33770116 DOI: 10.1371/journal.pone.0249343
Khurana N, Pulsipher A, Ghandehari H, Alt JA. Meta-analysis of global and high throughput public gene array data for robust vascular gene expression discovery in chronic rhinosinusitis: Implications in controlled release. J Control Release. 2021;330:878-888.
PMID: 33144181 DOI: 10.1016/j.jconrel.2020.10.061
2020
Jensen MM, Barber ZB, Khurana N, Isaacson KJ, Steinhauff D, Green B, Cappello J, Pulsipher A, Ghandehari H, Alt JA. A dual-functional Embolization-Visualization System for Fluorescence image-guided Tumor Resection. Theranostics. 2020;10(10):4530-4543.
PMID: 32292513 DOI: 10.7150/thno.39700
Sumsion JS, Pulsipher A, Alt JA. Differential expression and role of S100 proteins in chronic rhinosinusitis. Curr Opin Allergy Clin Immunol. 2020;20(1):14-22.
PMID: 31644435 DOI: 10.1097/ACI.0000000000000595
Orb Q, Pulsipher A, Smith KA, Ashby S, Alt JA. Correlation between systemic inflammatory response and quality of life in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol. 2019;9(5):458-465.
PMID: 30657646 DOI: 10.1002/alr.22289
Alt JA, Lee WY, Davis BM, Savage JR, Kennedy TP, Prestwich GD, Pulsipher A. A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis. PLoS One. 2018;13(9):e0204709.
PMID: 30252910 DOI: 10.1371/journal.pone.0204709
Pulsipher A, Davis BM, Smith KA, Ashby S, Qin X, Firpo M, Orlandi RR, Alt JA. Calgranulin C (S100A12) Is Differentially Expressed in Subtypes of Chronic Rhinosinusitis. Am J Rhinol Allergy. 2018;32(5):380-387.
PMID: 29943619 DOI: 10.1177/1945892418782238
Smith KA, Pulsipher A, Gabrielsen DA, Alt JA. Biologics in Chronic Rhinosinusitis: An Update and Thoughts for Future Directions. Am J Rhinol Allergy. 2018;32(5):412-423.
PMID: 30021447 DOI: 10.1177/1945892418787132
Thomas AJ, Pulsipher A, Davis BM, Alt JA. LL-37 causes cell death of human nasal epithelial cells, which is inhibited with a synthetic glycosaminoglycan. PLoS One. 2017;12(8):e0183542.
PMID: 28837619 DOI: 10.1371/journal.pone.0183542
Pulsipher A, Qin X, Thomas AJ, Prestwich GD, Oottamasathien S, Alt JA. Prevention of sinonasal inflammation by a synthetic glycosaminoglycan. Int Forum Allergy Rhinol. 2017;7(2):177-184.
PMID: 27863138 DOI: 10.1002/alr.21865
Dormán G, Nakamura H, Pulsipher A, Prestwich GD. The Life of Pi Star: Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore. Chem Rev. 2016;116(24):15284-15398.
PMID: 27983805 DOI: 10.1021/acs.chemrev.6b00342
Savage JR, Pulsipher A, Rao NV, Kennedy TP, Prestwich GD, Ryan ME, Lee WY. A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis. PLoS One. 2016;11(6):e0157310.
PMID: 27308827 DOI: 10.1371/journal.pone.0157310
2015
Alt JA, Qin X, Pulsipher A, Orb Q, Orlandi RR, Zhang J, Schults A, Jia W, Presson AP, Prestwich GD, Oottamasathien S. Topical cathelicidin (LL-37) an innate immune peptide induces acute olfactory epithelium inflammation in a mouse model. Int Forum Allergy Rhinol. 2015;5(12):1141-50.
PMID: 26346056 DOI: 10.1002/alr.21634
Luo W, Westcott N, Dutta D, Pulsipher A, Rogozhnikov D, Chen J, Yousaf MN. A Dual Receptor and Reporter for Multi-Modal Cell Surface Engineering. ACS Chem Biol. 2015;10(10):2219-26.
PMID: 26204094 DOI: 10.1021/acschembio.5b00137
Pulsipher A, Griffin ME, Stone SE, Hsieh-Wilson LC. Long-lived engineering of glycans to direct stem cell fate. Angew Chem Int Ed Engl. 2015;54(5):1466-70.
PMID: 25476911 DOI: 10.1002/anie.201409258
Dutta D, Pulsipher A, Luo W, Yousaf MN. PI3 kinase enzymology on fluid lipid bilayers. Analyst. 2014;139(20):5127-33.
PMID: 25133271 DOI: 10.1039/c4an00998c
Luo W, Pulsipher A, Dutta D, Lamb BM, Yousaf MN. Remote control of tissue interactions via engineered photo-switchable cell surfaces. Sci Rep. 2014;4:6313.
PMID: 25204325 DOI: 10.1038/srep06313
Pulsipher A, Dutta D, Luo W, Yousaf MN. Cell-surface engineering by a conjugation-and-release approach based on the formation and cleavage of oxime linkages upon mild electrochemical oxidation and reduction. Angew Chem Int Ed Engl. 2014;53(36):9487-92.
PMID: 25045145 DOI: 10.1002/anie.201404099
Pulsipher A, Griffin ME, Stone SE, Brown JM, Hsieh-Wilson LC. Directing neuronal signaling through cell-surface glycan engineering. J Am Chem Soc. 2014;136(19):6794-7.
PMID: 24746277 DOI: 10.1021/ja5005174
Dutta D, Pulsipher A, Luo W, Mak H, Yousaf MN. Engineering cell surfaces via liposome fusion. Bioconjug Chem. 2011;22(12):2423-33.
PMID: 22054009 DOI: 10.1021/bc200236m
Dutta D, Pulsipher A, Luo W, Yousaf MN. Synthetic chemoselective rewiring of cell surfaces: generation of three-dimensional tissue structures. J Am Chem Soc. 2011;133(22):8704-13.
PMID: 21561150 DOI: 10.1021/ja2022569
Pulsipher A, Yousaf MN. A renewable, chemoselective, and quantitative ligand density microarray for the study of biospecific interactions. Chem Commun. 2011;47(1):523-5.
PMID: 21052581 DOI: 10.1039/c0cc01509a
2010
Dutta D, Pulsipher A, Yousaf MN. Selective tethering of ligands and proteins to a microfluidically patterned electroactive fluid lipid bilayer array. Langmuir. 2010;26(12):9835-41.
PMID: 20131880 DOI: 10.1021/la1001545
Pulsipher A, Yousaf MN. Surface chemistry and cell biological tools for the analysis of cell adhesion and migration. Chembiochem. 2010;11(6):745-53, 730.
PMID: 20198673 DOI: 10.1002/cbic.200900787
Pulsipher A, Westcott NP, Luo W, Yousaf MN. Rapid in situ generation of two patterned chemoselective surface chemistries from a single hydroxy-terminated surface using controlled microfluidic oxidation. J Am Chem Soc. 2009;131(22):7626-32.
PMID: 19445524 DOI: 10.1021/ja809380e
Luo W, Westcott NP, Pulsipher A, Yousaf MN. Renewable and optically transparent electroactive indium tin oxide surfaces for chemoselective ligand immobilization and biospecific cell adhesion. Langmuir. 2008;24(22):13096-101.
PMID: 18928305 DOI: 10.1021/la802775v
Westcott NP, Pulsipher A, Lamb BM, Yousaf MN. Expedient generation of patterned surface aldehydes by microfluidic oxidation for chemoselective immobilization of ligands and cells. Langmuir. 2008;24(17):9237-40.
PMID: 18672921 DOI: 10.1021/la802208v
Yue GE, Roper MG, Balchunas C, Pulsipher A, Coon JJ, Shabanowitz J, Hunt DF, Landers JP, Ferrance JP. Protein digestion and phosphopeptide enrichment on a glass microchip. Anal Chim Acta. 2006;564(1):116-22.
PMID: 17723369 DOI: 10.1016/j.aca.2005.11.003